I'd suggest you a) upgrade to the most recent version of Zimbra, b) upgrade to the most recent version of FF, c) remove all extensions/skins/add-ins from FF and try to recreate the problem.
You don't say which version of Zimbra this is nor which operating system? Is this also on a linux, mac or windows client? Does this behaviour happen with other browsers? As this issue 'just appeared' it would lead me to believe you've updated something that's causing this problem, particularly as you say a browser refresh fixes it. You could also search through
bugzilla to see if there's any reported problems in this area.