As Vavai said, you can add rules to the salocal.cf.in file. I have both Whitelist, and Blacklist rules in the file for various sites.
one of our runls for example is;
Code:
#
rawbody LOCAL_ANGEL1 /\.angelfire\.com/i
describe LOCAL_ANGEL1 Watch sales
score LOCAL_ANGEL1 5.5
#
The score and our local spam % will move this to junk for this rule, use a smaller or larger score based on how much you like, or don't like the matched content.