After I tweaked my search terms Google found me a page recommending this:
As user 'zimbra':
Code:
% zmlocalconfig -e postfix_hopcount_limit=<blah>
and to make it effective immediately:
Code:
% postconf -e hopcount_limit=<blah>
Which should solve my problem. However, looking into it further it was my spam filter that was causing the problem, and the default hopcount_maximum for postfix and Zimbra appears to be 50.
Thanks again,
Josh