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I have some deleted accounts but still I am seeing emails are coming to that deleted email id .Is there any way so that we can give message to sender that this email accounts has been deleted from our domain.
Why? You will just be notifying spammers of that fact
If you really want to do that then one way would be to setup a generic account called "DeletedEmailAccount", add a Out of Office message to say that the account has been deleted, and then add all of your deleted accounts as aliases.
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Custom meassge for deleted email accounts 
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