Morning All

Getting massive server load under 5.0.1 (again)

Code:
top - 12:50:47 up 12 days,  1:50,  1 user,  load average: 50.47, 48.71, 47.45
Tasks: 248 total,   7 running, 241 sleeping,   0 stopped,   0 zombie
Cpu(s): 66.1% us, 33.5% sy,  0.0% ni,  0.0% id,  0.0% wa,  0.1% hi,  0.3% si
Mem:  12302208k total, 12025524k used,   276684k free,   440668k buffers
Swap:  8388600k total,      208k used,  8388392k free,  5270312k cached

  PID USER      PR  NI %CPU    TIME+  %MEM  VIRT  RES  SHR S COMMAND           
30599 zimbra    16   0  243   5083:51 16.0 4268m 1.9g  10m S java               
29869 zimbra    16   0   22  59:56.11  0.2  132m  26m 4172 S mysqld             
16375 zimbra    17   0   13   0:03.47  0.3  442m  39m 9040 S java               
16513 zimbra    16   0   11   0:01.53  0.3  442m  30m 8904 S java               
16597 zimbra    16   0   10   0:01.50  0.2  440m  29m 8892 S java               
16623 zimbra    16   0   10   0:00.67  0.2  437m  23m 8676 S java               
16831 zimbra    17   0   10   0:01.19  0.2  438m  26m 8864 S java               
16169 zimbra    17   0    9   0:02.12  0.3  442m  35m 8980 S java               
16690 zimbra    17   0    8   0:00.45  0.2  435m  19m 8308 S java               
16199 zimbra    16   0    7   0:00.39  0.2 41904  22m 2212 R zmlogprocess       
16430 zimbra    16   0    6   0:01.08  0.2  438m  25m 8864 S java               
16323 zimbra    16   0    5   0:03.45  0.3  443m  39m 9032 S java               
16779 zimbra    16   0    5   0:00.16  0.1  428m  11m 6672 S java               
11657 postfix   15   0    2   0:02.39  0.0 42916 4420 3352 R smtpd              
16941 zimbra    19   0    2   0:00.07  0.1 1195m  10m 6516 S java               
16908 zimbra    20   0    2   0:00.06  0.1 1195m  10m 6516 S java               
30213 zimbra    16   0    1 130:26.33 13.3 1705m 1.6g 4788 S mysqld             
 5937 postfix   15   0    1   0:04.01  0.0 42916 4432 3356 S smtpd              
16655 zimbra    19   0    1   0:01.27  0.2  440m  28m 8856 S java
Is there anything that can be done to reduce this, it is impacting the performance of mail delivery and causing delays.

I've logged a support ticket as well, but wanted to know if anyone else is experiencing anything similar. (or am I just the lucky one...)