I don't think that would have any effect on the issue you are seeing. If nginx and memcached are running, then something else is wrong, but it is quite unlikely to be a permissions issue.
Have you looked in /opt/zimbra/log/nginx.log? Have you looked in /var/log/zimbra.log?
--Quanah
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Quanah Gibson-Mount
Principal Software Engineer
Zimbra, Inc
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