I don't think it's too difficult to host multiple domains with Apache but someone with more experience can give you a more details answer.
If the CentOS install is cheaper per month then I'd go with that (it's not supported for NE but it's fine - I use it for my own server), it's binary compatible with RHEL. There's a couple of requirements to check (have a search of the wiki & forums) but nothing dramatic.
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Regards
Bill
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